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N'-((Dimethylamino)methylene)-N,N-dimethylformohydrazonamidedihydrochloride

Chinese Name: N'-((二甲基氨基)甲基)-N,N-二甲基甲腙盐酸盐
English Name: N'-((Dimethylamino)methylene)-N,N-dimethylformohydrazonamide dihydrochloride
CAS: 16227-06-8
Purity Specification: 98.0%
Product Category: Intermediate

Chinese Synonyms: N'-((二甲基氨基)甲基)-N,N-二甲基甲腙盐酸盐; 1,2-二[(二甲基氨基)亚甲基]肼二盐酸盐; N'-((二甲基氨基)甲基)-N,N-二甲基甲腙二盐酸盐

English Synonyms: N'-((Dimethylamino)methylene)-N,N-dimethylformohydrazonamide dihydrochloride; Methanehydrazonamide, N'-[(dimethylamino)methylene]-N,N-dimethyl-, hydrochloride(1:2)

CAS Number: 16227-06-8
Molecular Formula: C6H16Cl2N4
Molecular Weight: 215.12404

Keywords: 16227-06-8; N'-((Dimethylamino)methylene)-N,N-dimethyl-

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N1,N2-bis(4-hydroxy-2,6-dimethylphenyl)oxalamide

Chinese Name: N1,N2-双(4-羟基-2,6-二甲基苯基)草酰胺 (for reference only, please refer to the English name as official)
English Name: N1,N2-bis(4-hydroxy-2,6-dimethylphenyl)oxalamide
CAS: 1809288-95-6
Purity Specification: 98.0%
Product Category: Intermediate

Molecular Formula: C₁₈H₂₀N₂O₄
Molecular Weight: 328.36

Keywords: 1809288-95-6; copper-catalyzed hydrolysis ligand

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Nafamostat mesilate

Product Name: Nafamostat Mesilate

CAS No.: 82956-11-4
Purity: ≥99.0%
Category: API (Active Pharmaceutical Ingredient)
Shelf Life: 1 year
Storage: Store in a cool, dry place away from light
Molecular Formula: C₁₉H₁₇N₅O₂·(CH₄O₃S)₂
Molecular Weight: 539.58

Description

Nafamostat mesilate is a synthetic serine protease inhibitor. It exhibits potent inhibition against trypsin, plasmin, kallikrein, and components of the complement system (C1r, C1s), and has shown efficacy in treating acute pancreatitis by reducing pancreatic enzyme activity and mortality rates in animal models.

Application & Indications

  • Acute pancreatitis

  • Postoperative pancreatitis or pancreatitis after pancreatic duct imaging

  • Disseminated intravascular coagulation (DIC)

  • Prevention of coagulation during extracorporeal circulation

Market Background

First approved in Japan in 1986 by Japan Tobacco, Nafamostat has become a widely used treatment for acute pancreatitis. Its ability to selectively inhibit activated enzymes involved in inflammation and coagulation makes it a key drug in emergency and critical care.

Form: Lyophilized powder for injection (10mg per vial)
Regulatory Classification: Chemical Drug Class 3.1

Keywords: 82956-11-4; Nafamostat mesilate; Nafamostat; Serine protease inhibitor; Acute pancreatitis treatment

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Nafamostat mesylate

Chinese Name: 萘莫司他甲磺酸盐
English Name: Nafamostat mesylate
CAS Number: 82956-11-4
Purity Specification: 99.0%; JP16 (Japanese Pharmacopoeia 16th Edition)
Product Category: API (Active Pharmaceutical Ingredient)

Synonyms / Aliases:

  • 6-Amidino-2-naphthyl 4-guanidino-benzoate dimethanesulphonate

  • 6-脒基-2-萘基 4-胍基苯甲酸酯甲基磺酸盐

Molecular Formula:

  • C₁₉H₁₇N₅O₂·2(CH₄O₃S)

  • Or as an alternative representation: C₂₁H₂₅N₅O₈S₂

Molecular Weight: 539.58

CAS Registry Number: 82956-11-4

Keywords:
82956-11-4; 82957-06-0; Nafamostat mesylate; Nafamostat

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Naltrexone

English Name: Naltrexone
Alias: 17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
Product Name: Naltrexone; Nacaltrexone; 17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one

Molecular Structure: CAS Registry Number: 16590-41-3, Naltrexone, Nacaltrexone, 17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
Molecular Formula: C20H23NO4
Molecular Weight: 341.40
CAS Registry Number: 16590-41-3
EC Number: 240-649-9

关键字： 16590-41-3;Naltrexone;纳曲酮;

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NASH

English Name: NASH
Chinese Name: 化合物NASH
CAS Number: 1099592-35-4
Purity Specification: 98.0%
Product Category: Intermediate

Molecular Formula: C18H14N2O3
Molecular Weight: 306.32 g/mol
CAS Registry Number: 1099592-35-4

Alias:

  • 2-hydroxy-N-[(E)-(2-hydroxynaphthalen-1-yl)methylideneamino]benzamide

Structure:

  • CAS Registry Number: 1099592-35-4, Naphthyl salicylamide hydrazone

Keywords: 1099592-35-4; NASH

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