Product Name: Clemastine Fumarate
CAS No.: 14976-57-9
Purity: ≥99.0%
Category: API (Active Pharmaceutical Ingredient)
Shelf Life: 1 year
Storage: Store in a cool, dry place away from light
Appearance: White or off-white crystalline powder
Molecular Formula: –
Molecular Weight: –
Solubility: Slightly soluble in methanol, very slightly soluble in water and chloroform
Specific Rotation: +15° to +18° (in methanol, approx. 10 mg/ml)
Pharmacological Action:
Clemastine Fumarate is a second-generation H1 receptor antagonist developed by Sandoz in the 1960s. It has been widely used in the U.S., Japan, and Germany for the treatment of histamine-induced allergic diseases. It is fast-acting, long-lasting, and highly effective with minimal drowsiness.
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Onset of Action: ~30 minutes
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Duration: Up to 12 hours
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Main Uses: Allergic rhinitis, urticaria, eczema, and other allergic skin conditions
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Clinical Efficacy:
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98% effective for allergic rhinitis
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61.3% cure rate for chronic urticaria
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10× stronger than chlorpheniramine
Keywords: 14976-57-9; Clemastine Fumarate; Clemastine; Antihistamine; H1 antagonist