Shop

You are here:
  1. Home
  2. Shop
  3. Page 14
Categories
Price

Showing 79–84 of 229 results

Categories & Filter

Baricitinib

Product Name: Baricitinib
CAS No.: 1187594-09-7
Purity: ≥99.0%
Category: API (Active Pharmaceutical Ingredient)
Shelf Life: 1 year
Storage: Room temperature, protect from light

Molecular Formula: C16H17N7O2S
Molecular Weight: 371.42

Indication:
Baricitinib is used for the treatment of moderate to severe rheumatoid arthritis (RA).

Mechanism of Action:
A selective JAK1 and JAK2 inhibitor, with IC50 values of 5.9 nM and 5.7 nM respectively. It shows ~70-fold and ~10-fold selectivity over JAK3 and Tyk2, with no inhibitory activity on c-Met or Chk2.

Approval Status:
Originally developed by Incyte and co-developed with Eli Lilly.

  • EMA approved (Feb 14, 2017) under the brand name Olumiant.

  • NDA submitted to FDA in January 2016.

Keywords: 1187594-09-7; Baricitinib; Olumiant; JAK inhibitor; rheumatoid arthritis treatment

Add to Quote

Benzoicacid,4-[5-(3,5-dichloro-4-fluorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-2-methyl-

English Name: Benzoic acid, 4-[5-(3,5-dichloro-4-fluorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-2-methyl-

English Synonyms: Benzoic acid, 4-[5-(3,5-dichloro-4-fluorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-2-methyl-; 4-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-2-methylbenzoic acid; 4-[5-(3,5-Dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-3-isoxazolyl]-2-methylbenzoic Acid; CCMO-48

CAS Number: 1332698-41-5

Molecular Formula: C18H11Cl2F4NO3

Molecular Weight: 436.18

Add to Quote

Besifloxacin hydrochloride

Product Name: Besifloxacin Hydrochloride

CAS No.: 405165-61-9
Purity: ≥99%
Shelf Life: 1 year
Storage: Store in a cool, dry place away from light
Brand: Chenxi Pharma
Origin: Jinan, China
Category: API (Active Pharmaceutical Ingredient)

Description

Besifloxacin hydrochloride is a next-generation fluoroquinolone antibiotic developed by Bausch & Lomb. Approved by the FDA in May 2009, it is the first fluoroquinolone specifically developed for ophthalmic use. Marketed under the brand name Besivance, it is formulated as a 0.6% ophthalmic suspension for treating bacterial conjunctivitis.

Mechanism of Action

Besifloxacin exerts its bactericidal activity by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication and cell division. It is effective against a broad spectrum of Gram-positive and Gram-negative pathogens.

Clinical Efficacy

Clinical trials involving over 2400 patients demonstrated:

  • 80% bacterial eradication rate

  • High efficacy in both adults and children (≥1 year)

  • Low incidence of adverse effects (<3%), primarily mild ocular symptoms

Regulatory & Market Status

  • Patented: WO2008091752, US2008176834

  • Launched in the USA

  • Clinical approval granted in China (June 2010)

Keywords: 405165-61-9; Besifloxacin Hydrochloride; Besivance; Fluoroquinolone ophthalmic antibiotic

Add to Quote

Bisoxatin acetate

English Name: Bisoxatin acetate
Product Name: Bisoxatin acetate; Bisoxatin ethyl ester; Compound T30476L

Molecular Structure: CAS Registry Number: 14008-48-1, Bisoxatin acetate
Molecular Formula: C24H19NO6
Molecular Weight: 417.41
CAS Registry Number: 14008-48-1
EC Number: 237-820-5

Add to Quote

Carboplatin

English Name: Carboplatin
Alias: 1,1-Cyclobutanedicarboxylatodiammineplatinum (II); Paraplatin; cis-Diamine(1,1-cyclobutanedicarboxylato)platinum(II)
Product Name: Carboplatin; cis-1,1-Cyclobutanedicarboxylic acid diammine platinum

Molecular Structure: CAS Registry Number: 41575-94-4, Carboplatin, cis-1,1-Cyclobutanedicarboxylic acid diammine platinum
Molecular Formula: C6H12N2O4Pt
Molecular Weight: 371.25
CAS Registry Number: 41575-94-4
EC Number: 255-446-0

Add to Quote

Carteolol hydrochloride

Product Name: Carteolol Hydrochloride
CAS Number: 51781-21-6
Purity: 99.0% (HPLC)
Product Category: API (Active Pharmaceutical Ingredient)

Chemical Name:
5-(3-tert-Butylamino-2-hydroxy)propoxy-3,4-dihydrocarbostyril hydrochloride

Synonyms:

  • Carteolol HCl

  • Carteolol

  • Endak

  • Mikelan

  • Ocupress

  • Teoptic

  • NSC 300906

  • OPC 1085

Molecular Formula: C16H24N2O3·HCl
Molecular Weight: 328.83
EINECS: 257-415-7

Keywords:
51781-21-6; Carteolol hydrochloride; Carteolol; Carteolol HCl; 30389-33-4

Add to Quote