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Tadalafil

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CAS:171596-29-5

Indications: Erectile dysfunction and pulmonary hypertension

Pharmacology: It is a selective reversible inhibitor of guanosine cyclophosphate (cGMP)-specific phosphodiesterase 5 (PDE5).When sexual stimulation leads to the local release of nitric oxide, PDE5 is inhibited by tadalafil, which increases the level of cGMP in the cavernous body of the penis, which leads to relaxation of smooth muscles and blood flowing into the penis tissue to produce an erection, such as asexual stimulation.