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2-(2,6-Dioxopiperidin-3-yl)-4-fluoro-2,3-dihydro-1H-isoindole-1,3-dione

Product Name:
2-(2,6-Dioxopiperidin-3-yl)-4-fluoro-2,3-dihydro-1H-isoindole-1,3-dione

Chinese Name:
2-(2,6-二氧代哌啶-3-基)-4-氟-2,3-二氢-1H-异吲哚-1,3-二酮

CAS Number:
835616-60-9

Purity:
99.0%

Category:
Pharmaceutical Intermediate


Synonyms:

  • 2-(2,6-Dioxopiperidin-3-yl)-4-fluoroisoindolin-1,3-dione

  • 2-(2,6-Dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione

  • 4-Fluoro-thalidomide

Molecular Formula:
C₁₃H₉FN₂O₄

Molecular Weight:
276.22 g/mol


Chemical Structure Highlights:
This compound features a fluorinated isoindoline-1,3-dione core with a 2,6-dioxopiperidin-3-yl substituent, structurally related to thalidomide analogs. It serves as a key intermediate in the synthesis of immunomodulatory drugs (IMiDs) and cereblon E3 ligase modulators (CELMoDs).


Applications:
Used in pharmaceutical research and development, particularly in the synthesis of potential anticancer or immunotherapy agents.


Keywords:
835616-60-9; 4-Fluoro-thalidomide; IMiD intermediate; CELMoD building block; Fluorinated isoindoline derivative