Pharmaceutical Intermediates

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TAK-788

Chinese Name: TAK788
English Name: TAK-788
Purity: 99.0%
Product Category: Intermediate

Background Information:
On January 15, 2020, the Center for Drug Evaluation (CDE) of the China National Medical Products Administration (NMPA) announced that TAK-788, developed by Takeda, has received implicit clinical trial approval in China.
TAK-788 is a next-generation, potent, and selective small molecule tyrosine kinase inhibitor (TKI), specifically developed to treat non-small cell lung cancer (NSCLC) patients with EGFR exon 20 insertion mutations.

Keywords:
TAK788; TAK-788; AP 32788

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TATM

Chinese Name: 三氟甘露糖
English Name: TATM
CAS Number: 92051-23-5
Purity: 99.0%
Product Category: Intermediate

Chinese Synonyms:

  • 甘露糖三氟磺酸酯

  • 1,3,4,6-四乙酰-2-三氟甲烷磺酰-β-D-吡喃甘露糖

  • 1,3,4,6-O-四乙酰基-2-O-三氟甲磺酰基-β-D-吡喃甘露糖

  • 四-邻-乙酰基-2-三氟甲烷-黄酰基吡喃甘露糖

English Synonyms:

  • BETA-D-Mannopyranose 1,3,4,6-tetraacetate 2-triflate

  • 1,3,4,6-Tetra-O-acetyl-2-O-trifluoromethanesulfonyl-β-D-mannopyranose

  • 1,3,4,6-Tetra-O-acetyl-2-O-trifluoromethylsulphonyl-β-D-mannopyranose

  • Mannose triflate

Molecular Formula: C₁₅H₁₉F₃O₁₂S
Molecular Weight: 480.36

EINECS Number: Not available
Structure File: Available as 92051-23-5.mol

Keywords:
92051-23-5; TATM; Mannose triflate; 三氟甘露糖; 甘露糖三氟磺酸酯

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TDI-011536

Product Name: TDI-011536
Chinese Name: TDI-011536
CAS Number: 2687970-96-1
Purity: ≥98.0%
Product Category: Intermediate
Molecular Formula: C19H16N4O2S
Molecular Weight: 364.42 g/mol

Physical Properties:

  • Density: N/A

  • Boiling Point: N/A

  • Melting Point: N/A

  • Flash Point: N/A

  • MSDS: N/A

Structure:

  • Structure of TDI-011536: [Image representation could be added here]

Applications:

TDI-011536 is used in pharmaceutical and medicinal chemistry research, specifically as an intermediate for the development of pharmaceutical compounds with potential therapeutic applications.

Keywords:

2687970-96-1; TDI-011536

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Thioacetamide

English Name: Thioacetamide
Alias: Ethanethioamide
Product Name: Thioacetamide
Purity Specification: 98.0%
Product Category: Intermediate
Grade: Pharmaceutical Grade

Molecular Structure: CAS Registry Number: 62-55-5, Thioacetamide
Molecular Formula: C2H5NS
Molecular Weight: 75.13
CAS Registry Number: 62-55-5
EINECS Registry Number: 200-541-4

Melting Point: 108-112°C (lit.)
Boiling Point: 111.7±23.0°C (Predicted)
Density: 1.37
Refractive Index: 1.5300 (estimate)
Storage Conditions: Inert atmosphere, Room temperature
Acidity Constant (pKa): 13.25±0.29 (Predicted)
Appearance: Liquid
Color: Grayish-white to light beige

Keywords: 62-55-5; Thioacetamide

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trans-1,2-Cyclohexanediamine-N,N,N',N'-tetraacetic acid monohydrate

English Name: trans-1,2-Cyclohexanediamine-N,N,N',N'-tetraacetic acid monohydrate
Alias: trans-(±)-N,N'-1,2-Cyclohexanediylbis[N-(carboxymethyl)glycine monohydrate
Product Name: trans-1,2-Cyclohexanediamine-N,N,N',N'-tetraacetic acid monohydrate

Molecular Structure: CAS Registry Number: 125572-95-4, trans-1,2-Cyclohexanediamine-N,N,N',N'-tetraacetic acid monohydrate
Molecular Formula: C14H22N2O8·H2O
Molecular Weight: 364.35
CAS Registry Number: 125572-95-4
EC Number: 681-197-6

keyword： 125572-95-4;

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Trimethyloxosulfonium chloride

English name: Trimethyloxosulfonium chloride
Alias: Trimethylsulfoxonium chloride
Product name: Trimethyloxosulfonium chloride

Molecular structure: CAS Registry number: 5034-06-0, Trimethyloxosulfonium chloride

Molecular formula: C3H9OS.Cl
Molecular weight: 128.62
CAS Registry number: 5034-06-0
EINECS Registry number: 225-724-6

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