Pharmaceutical Intermediates

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11-Bromoundecanoic acid methyl ester

Chinese Name: 11-溴十一烷酸甲酯
English Name: 11-Bromoundecanoic acid methyl ester
CAS: 6287-90-7
Purity Specification: 98.0%
Product Category: Intermediate

English Name: 11-Bromoundecanoic acid methyl ester
Alias: Methyl 11-bromoundecanoate; NSC 12015
Product Name: 11-溴十一烷酸甲酯

Molecular Formula: C₁₂H₂₃BrO₂
Molecular Weight: 279.21
CAS Registration Number: 6287-90-7

Keywords: 6287-90-7; 11-溴十一烷酸甲酯; NSC 12015

1H-Isoindole-1,3(2H)-dione,2-(2,6-dioxo-3-piperidinyl)-5-fluoro-

Chinese Name: 2-(2,6-二氧代-哌啶-3-基)-5-氟-异吲哚-1,3-二酮
English Name: 2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione
CAS Number: 835616-61-0
Purity: 98.0%
Product Category: Intermediate


Chinese Synonyms:

  • 2-(2,6-二氧亚基哌啶-3-基)-5-氟异二氢吲哚-1,3-二酮

  • 4-氟沙度利安

English Synonyms:

  • 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-

  • 2-(2,6-Dioxo-3-piperidinyl)-5-fluoro-1H-isoindole-1,3(2H)-dione

  • 135588


Molecular Formula: C₁₃H₉FN₂O₄
Molecular Weight: 276.22

CAS Registry Number: 835616-61-0
(Note: 835616-60-9 and 319-03-0 are listed as related keywords but refer to different compounds.)


Keywords:
835616-61-0; 835616-60-9; 319-03-0; 2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione; 4-氟沙度利安

2-(2-(4-methylthiazol-5-yl)ethoxy)-2-oxoethyl)triphenylphosphonium bromide

Chinese Name: TPP-噻唑
English Name: 2-(2-(4-methylthiazol-5-yl)ethoxy)-2-oxoethyl)triphenylphosphonium bromide
CAS: 1352002-58-4
Purity Specification: 99.0%
Product Category: Intermediate

Synonyms:

  • TPP-thiazole

  • 2-(2-(4-methylthiazol-5-yl)ethoxy)-2-oxoethyl)triphenylphosphonium bromide

Molecular Formula: Not explicitly provided, but can be derived from the name.
(Please let me know if you need the exact molecular formula and weight calculated.)

CAS Registration Number: 1352002-58-4

Keywords: 1352002-58-4; TPP-噻唑; TPP-thiazole

2-(2,6-Dioxopiperidin-3-yl)-4-fluoro-2,3-dihydro-1H-isoindole-1,3-dione

Product Name:
2-(2,6-Dioxopiperidin-3-yl)-4-fluoro-2,3-dihydro-1H-isoindole-1,3-dione

Chinese Name:
2-(2,6-二氧代哌啶-3-基)-4-氟-2,3-二氢-1H-异吲哚-1,3-二酮

CAS Number:
835616-60-9

Purity:
99.0%

Category:
Pharmaceutical Intermediate


Synonyms:

  • 2-(2,6-Dioxopiperidin-3-yl)-4-fluoroisoindolin-1,3-dione

  • 2-(2,6-Dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione

  • 4-Fluoro-thalidomide

Molecular Formula:
C₁₃H₉FN₂O₄

Molecular Weight:
276.22 g/mol


Chemical Structure Highlights:
This compound features a fluorinated isoindoline-1,3-dione core with a 2,6-dioxopiperidin-3-yl substituent, structurally related to thalidomide analogs. It serves as a key intermediate in the synthesis of immunomodulatory drugs (IMiDs) and cereblon E3 ligase modulators (CELMoDs).


Applications:
Used in pharmaceutical research and development, particularly in the synthesis of potential anticancer or immunotherapy agents.


Keywords:
835616-60-9; 4-Fluoro-thalidomide; IMiD intermediate; CELMoD building block; Fluorinated isoindoline derivative

2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione

Chinese Name:
2-(2,6-二氧代-哌啶-3-基)-4-羟基-异吲哚-1,3-二酮

English Name:
2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione

CAS Number: 5054-59-1
Purity: 98.0%
Product Category: Intermediate


Chinese Synonyms:

  • 扑尔敏胺杂质1

  • 沙利度胺杂质

  • 2-(2,6-二氧代-3-哌啶基)-4-羟基异吲哚啉-1,3-二酮

  • 2-(2,6-二氧代哌啶-3-基)-4-羟基异吲哚啉-1,3-二酮

English Synonyms:

  • 4-HydroxyThalidomide

  • 2-(2,6-Dioxopiperidin-3-yl)-4-hydroxy-isoindole-1,3-dione

  • 2-(2,6-dioxopiperidin-3-yl)-4-hydroxy-2,3-dihydro-1H-isoindole-1,3-dione

  • Pomalidomide Impurity 15

  • Thalidomide Impurity 1

  • E3 ligase ligand 2


Molecular Formula: C₁₃H₁₀N₂O₅
Molecular Weight: 274.23

Structure: (Referenced under CAS No. 5054-59-1)

Keywords:
5054-59-1; 37418-88-5; 3-羟基邻苯二甲酸酐; Thalidomide Impurity; Pomalidomide Impurity

2-(3-Pyridylmethylene)-1,3-indandione

Product Name: PRT4165
Chinese Name: PRT4165
CAS Number: 31083-55-3
Purity: ≥98.0%
Product Category: Intermediate
Grade: Pharmaceutical Grade


Synonyms:

  • NSC 600157

  • 2-(3-Pyridylmethylene)-1,3-indandione


Chemical Information:

  • Molecular Formula: C15H9NO2

  • Molecular Weight: 235.24 g/mol

  • Structure: ![Structure not shown; can be added as image if needed]


Applications:

PRT4165, also known as NSC 600157, is used in medicinal chemistry research and can serve as an intermediate for the development of novel pharmaceutical compounds with potential biological activity.


Keywords:

31083-55-3; PRT4165; NSC 600157