Product Name:
2-(2,6-Dioxopiperidin-3-yl)-4-fluoro-2,3-dihydro-1H-isoindole-1,3-dione
Chinese Name:
2-(2,6-二氧代哌啶-3-基)-4-氟-2,3-二氢-1H-异吲哚-1,3-二酮
CAS Number:
835616-60-9
Purity:
99.0%
Category:
Pharmaceutical Intermediate
Synonyms:
-
2-(2,6-Dioxopiperidin-3-yl)-4-fluoroisoindolin-1,3-dione
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2-(2,6-Dioxopiperidin-3-yl)-4-fluoroisoindoline-1,3-dione
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4-Fluoro-thalidomide
Molecular Formula:
C₁₃H₉FN₂O₄
Molecular Weight:
276.22 g/mol
Chemical Structure Highlights:
This compound features a fluorinated isoindoline-1,3-dione core with a 2,6-dioxopiperidin-3-yl substituent, structurally related to thalidomide analogs. It serves as a key intermediate in the synthesis of immunomodulatory drugs (IMiDs) and cereblon E3 ligase modulators (CELMoDs).
Applications:
Used in pharmaceutical research and development, particularly in the synthesis of potential anticancer or immunotherapy agents.
Keywords:
835616-60-9; 4-Fluoro-thalidomide; IMiD intermediate; CELMoD building block; Fluorinated isoindoline derivative