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Ruxolitinib

English Name: Ruxolitinib
Alias: INCB-018424; (betaR)-beta-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile
Product Name: Ruxolitinib; Selective JAK1, JAK2 Protein Tyrosine Kinase Inhibitor
Purity Specification: 99.0%
Product Category: API
Grade: Pharmaceutical Grade

Molecular Structure: CAS Registry Number: 941678-49-5, Ruxolitinib, Selective JAK1, JAK2 Protein Tyrosine Kinase Inhibitor
Molecular Formula: C17H18N6
Molecular Weight: 306.36
CAS Registry Number: 941678-49-5

Keywords: 941678-49-5; Ruxolitinib; Ruxolitinib; Ruxolitinib

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Sorafenib tosylate

CAS code:475207-59-1

Indications:
An anticancer agent used for the treatment of liver and renal cell carcinoma.

Pharmacology:
Sorafenib is a multikinase inhibitor that inhibits tumor cell proliferation in vitro.

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STAT5-IN-1

Product Name: STAT5-IN-1
Chinese Name: MDK-6314
CAS Number: 285986-31-4
Purity Specification: 98.0%
Product Category: Intermediate

Synonyms:

  • MDK-6314

  • STAT5 Inhibitor

  • STAT5Inhibitor

  • STAT5-Inhibitor

  • MDK 6314

  • MDK6314

  • N-[(E)-(4-oxochromen-3-yl)methylideneamino]pyridine-3-carboxamide

Molecular Formula: C16H11N3O3
Molecular Weight: 293.28 g/mol

Structural Information:

  • SMILES: C1=CC=C2C(=C1)C(=O)C(=CO2)C=NNC(=O)C3=CN=CC=C3

  • InChI: 1S/C16H11N3O3/c20-15-12(10-22-14-6-2-1-5-13(14)15)9-18-19-16(21)11-4-3-7-17-8-11/h1-10H,(H,19,21)/b18-9+

  • InChIKey: DAVIKTBRCQWOGT-GIJQJNRQSA-N

Keywords:
STAT5-IN-1; 285986-31-4; MDK-6314

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Sunitinib malate

CAS code：341031-54-7

Indications:
Gastrointestinal stromal tumor (GIST) and advanced renal cell carcinoma.

Pharmacology:
A small molecule inhibitor of multiple receptor tyrosine kinases (RTKs), some of which are involved in tumor growth, pathological angiogenesis, and metastasis.

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Tadalafil

CAS：171596-29-5 Indications: Erectile dysfunction and pulmonary hypertension Pharmacology: It is a selective reversible inhibitor of guanosine cyclophosphate (cGMP)-specific phosphodiesterase 5 (PDE5).When sexual stimulation leads to the local release of nitric oxide, PDE5 is inhibited by tadalafil, which increases the level of cGMP in the cavernous body of the penis, which leads to relaxation of smooth muscles and blood flowing into the penis tissue to produce an erection, such as asexual stimulation.
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Tegoprazan

English Name: Tegoprazan
Alias: 7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-chromen-4-yl]oxy]-N,N,2-trimethyl-3H-benzimidazole-5-carboxamide
Product Name: Tegoprazan
Purity Specification: 99.0%
Product Category: API
Grade: Pharmaceutical Grade

Molecular Structure: CAS Registry Number: 942195-55-3, Tegoprazan
Molecular Formula: C20H19F2N3O3
Molecular Weight: 387.38
CAS Registry Number: 942195-55-3

SMILES: CC1=NC2=C(N1)C=C(C=C2O[C@H]3CCOC4=C3C(=CC(=C4)F)F)C(=O)N(C)C

Keywords: 942195-55-3; Tegoprazan; Tegoprazan

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