Active Pharmaceutical Ingredient

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Showing 97–102 of 136 results

Milbemycin oxime

Chinese Name: 米尔贝肟
English Name: Milbemycin oxime
CAS Number: 129496-10-2
Purity Specification: 99.0%
Product Category: API (Active Pharmaceutical Ingredient)
Grade: Pharmaceutical Grade
Alias: Milbemycin
Molecular Formula: 2C32H45NO7·2C31H43NO7   关键字: 129496-10-2;米尔贝肟;米尔贝霉素;

Mobocertinib succinate

Chinese Name: TAK788
English Name: Mobocertinib succinate
CAS Number: 2389149-74-8
Purity: 99.0%
Grade: Pharmaceutical Grade
Product Category: API (Active Pharmaceutical Ingredient)


Synonyms / Aliases:

  • Mobocertinib succinate

  • TAK-788 succinate

  • AP32788 succinate

  • AP-32788 succinate

  • TAK 788 succinate


Molecular Formula: C₃₆H₄₅N₇O₈
Molecular Weight: 703.78

Storage Conditions: Store at 4–8 °C


Keywords:
2389149-74-8; 1847461-43-1; TAK788; Mobocertinib; AP32788

N-Methyl-1-naphthalenemethylamine hydrochloride

English Name: N-Methyl-1-naphthalenemethylamine hydrochloride
Alias: Terbinafine Intermediate
Product Name: N-Methyl-1-naphthalenemethylamine hydrochloride
Purity Specification: 98.0%
Product Category: Intermediate
Grade: Pharmaceutical Grade

Molecular Structure: CAS Registry Number: 65473-13-4, N-Methyl-1-naphthalenemethylamine hydrochloride
Molecular Formula: C12H13N·HCl; C12H14ClN
Molecular Weight: 207.70
CAS Registry Number: 65473-13-4

Keywords: 65473-13-4; Terbinafine; Terbinafine hydrochloride; 78628-80-5

Nafamostat mesilate

Product Name: Nafamostat Mesilate

CAS No.: 82956-11-4
Purity: ≥99.0%
Category: API (Active Pharmaceutical Ingredient)
Shelf Life: 1 year
Storage: Store in a cool, dry place away from light
Molecular Formula: C₁₉H₁₇N₅O₂·(CH₄O₃S)₂
Molecular Weight: 539.58


Description

Nafamostat mesilate is a synthetic serine protease inhibitor. It exhibits potent inhibition against trypsin, plasmin, kallikrein, and components of the complement system (C1r, C1s), and has shown efficacy in treating acute pancreatitis by reducing pancreatic enzyme activity and mortality rates in animal models.


Application & Indications

  • Acute pancreatitis

  • Postoperative pancreatitis or pancreatitis after pancreatic duct imaging

  • Disseminated intravascular coagulation (DIC)

  • Prevention of coagulation during extracorporeal circulation


Market Background

First approved in Japan in 1986 by Japan Tobacco, Nafamostat has become a widely used treatment for acute pancreatitis. Its ability to selectively inhibit activated enzymes involved in inflammation and coagulation makes it a key drug in emergency and critical care.


Form: Lyophilized powder for injection (10mg per vial)
Regulatory Classification: Chemical Drug Class 3.1


Keywords: 82956-11-4; Nafamostat mesilate; Nafamostat; Serine protease inhibitor; Acute pancreatitis treatment

Nafamostat mesylate

Chinese Name: 萘莫司他甲磺酸盐
English Name: Nafamostat mesylate
CAS Number: 82956-11-4
Purity Specification: 99.0%; JP16 (Japanese Pharmacopoeia 16th Edition)
Product Category: API (Active Pharmaceutical Ingredient)


Synonyms / Aliases:

  • 6-Amidino-2-naphthyl 4-guanidino-benzoate dimethanesulphonate

  • 6-脒基-2-萘基 4-胍基苯甲酸酯甲基磺酸盐


Molecular Formula:

  • C₁₉H₁₇N₅O₂·2(CH₄O₃S)

  • Or as an alternative representation: C₂₁H₂₅N₅O₈S₂

Molecular Weight: 539.58

CAS Registry Number: 82956-11-4

Keywords:
82956-11-4; 82957-06-0; Nafamostat mesylate; Nafamostat

NASH

English Name: NASH
Chinese Name: 化合物NASH
CAS Number: 1099592-35-4
Purity Specification: 98.0%
Product Category: Intermediate

Molecular Formula: C18H14N2O3
Molecular Weight: 306.32 g/mol
CAS Registry Number: 1099592-35-4

Alias:

  • 2-hydroxy-N-[(E)-(2-hydroxynaphthalen-1-yl)methylideneamino]benzamide

Structure:

  • CAS Registry Number: 1099592-35-4, Naphthyl salicylamide hydrazone

Keywords: 1099592-35-4; NASH