Active Pharmaceutical Ingredient

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Erlotinib hydrochloride

CAS code: 183319-69-9

Indications:
Indicated for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) in patients who have failed at least one prior chemotherapy regimen.

Pharmacology:
Erlotinib is a tyrosine kinase inhibitor of the epidermal growth factor receptor (EGFR). It competitively binds to the intracellular catalytic domain of EGFR tyrosine kinase, blocking ATP binding, thereby inhibiting phosphorylation. This action disrupts downstream signaling pathways, ultimately preventing tumor growth and controlling cell proliferation, angiogenesis, and metastasis.

Ethyl 2-Amino-2-Cyanoacetate Oxalate Hydrate

Product Name: Ethyl 2-Amino-2-Cyanoacetate Oxalate Hydrate
English Name: Ethyl 2-Amino-2-Cyanoacetate Oxalate Hydrate
Alias: ETHYL 2-AMINO-2-CYANOACETATE1/2OXALATEH2O; ETHYL 2-AMINO-2-CYANOACETATE OXALATE H2O; Acetic Acid, Aminocyano-, Ethyl Ester

Molecular Structure: CAS Registry Number: 32683-02-6, Ethyl 2-Amino-2-Cyanoacetate Oxalate Hydrate
Molecular Formula: C5H8N2O2
Molecular Weight: 128.13
CAS Registry Number: 32683-02-6

Ethyl 4-Amino-5-Imidazolecarboxylate

Product Name: Ethyl 4-Amino-5-Imidazolecarboxylate
English Name: Ethyl 4-Amino-5-Imidazolecarboxylate
Alias: 5-Amino-3H-Imidazole-4-Carboxylic Acid Ethyl Ester; H-Imidazole-4-Carboxylic Acid, 5-Amino-, Ethyl Ester; Imidazole, 4-Amino-5-Ethoxycarbonyl-

Molecular Structure: CAS Registry Number: 21190-16-9, Ethyl 4-Amino-5-Imidazolecarboxylate
Molecular Formula: C6H9N3O2
Molecular Weight: 155.16
CAS Registry Number: 21190-16-9

Evodiamine

English Name: Evodiamine
Alias: 8,13,13b,14-Tetrahydro-14-methylindolo[2'3'-3,4]pyrido[2,1-b]quinazolin-5-[7H]-one
Product Name: Evodiamine

Molecular Structure: CAS Registry Number: 518-17-2, Evodiamine
Molecular Formula: C19H17N3O
Molecular Weight: 303.36
CAS Registry Number: 518-17-2
EC Number: 637-111-4

Firocoxib

English Name: Firocoxib
Alias: 3-(Cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone
Product Name: Firocoxib; 3-(Cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone
Purity Specification: 99.0%
Product Category: Intermediate
Grade: Pharmaceutical Grade

Molecular Structure: CAS Registry Number: 189954-96-9, Firocoxib, 3-(Cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone
Molecular Formula: C17H20O5S
Molecular Weight: 336.40
CAS Registry Number: 189954-96-9

Flometoquin

English Name: FLOMETOQUIN

English Synonyms: FLOMETOQUIN; Carbonic acid, 2-ethyl-3,7-dimethyl-6-[4-(trifluoromethoxy)phenoxy]-4-quinolinylmethyl ester; 2-Ethyl-3,7-dimethyl-6-(4-(trifluoromethoxy)phenoxy)quinolin-4-yl methyl carbonate

CAS Number: 875775-74-9

Molecular Formula: C22H20F3NO5

Molecular Weight: 435.39