High-Quality Tadalafil Intermediate (CAS 171489-59-1) – Trusted Manufacturer & API Supply Partner

Tadalafil Intermediate, with CAS No. 171489-59-1, is a vital building block in the synthesis of Tadalafil API—a potent PDE5 inhibitor widely used for the treatment of erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). As demand for generic Cialis™ formulations continues to grow globally, ensuring a reliable source of this intermediate is critical to pharmaceutical companies and API manufacturers.

At Yikang Chemical, we provide high-purity tadalafil intermediates tailored for GMP-compliant production, research use, and scale-up synthesis.


Product Specifications – Tadalafil Intermediate

  • Product Name: Tadalafil Intermediate
  • CAS Number: 171489-59-1
  • Molecular Formula: C14H15NO5
  • Molecular Weight: 277.27 g/mol
  • Purity: ≥98% (HPLC tested)
  • Appearance: White to off-white crystalline powder
  • Synonyms: Tadalafil key intermediate; cis-methyl 3-(1,3-benzodioxol-5-yl)-4-(methoxycarbonylamino)-4-oxobutanoate

This compound is typically involved in the early-stage condensation and cyclization steps leading to the formation of the tetracyclic core structure of Tadalafil.


🧪 Applications & Use Cases

  • Essential intermediate in Tadalafil synthesis
  • Pharmaceutical R&D and scale-up
  • CRO/CDMO custom synthesis projects
  • Generic drug manufacturing for PDE5 inhibitors

Our intermediate is suitable for pilot batches, process validation, and regulated market formulations, with supporting documents available for compliance and registration purposes.


🏭 Why Choose Yikang Chemical?

  • High Batch Purity – ≥98% by HPLC, minimal residual solvents
  • Full Documentation – COA, MSDS, synthesis route, impurity profile
  • Flexible MOQ – From grams to kilograms, with stable stock
  • Custom Synthesis Available – Route optimization and tech support
  • Fast Global Delivery – Secure packaging and export clearance

Our products are widely used by API manufacturers, generic pharmaceutical companies, and international R&D labs looking for reliable, cost-effective intermediates.


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📦 Packaging & Logistics

  • Standard Packing: Aluminum foil bag / sealed HDPE drum
  • MOQ: 100g for R&D; scalable to kilograms for production
  • Shipping Options: DHL, FedEx, air cargo, or sea freight
  • Storage: Cool, dry, sealed conditions to avoid moisture or light exposure

📞 Contact Us Now for COA, Sample or Quotation

Looking for a reliable tadalafil intermediate supplier with strong technical support and fast delivery? Get in touch with Yikang Chemical today to discuss your needs for R&D, formulation, or bulk production.

🌐 Website: www.yikanghuagong.com
📧 Email: yikangmelody@163.com

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