High-Purity Letermovir (CAS 917389-32-3) – Antiviral API for CMV Infection Treatment

Letermovir, with CAS No. 917389-32-3, is a breakthrough antiviral drug approved for the prophylaxis of cytomegalovirus (CMV) infection in adult patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT). As a non-nucleoside CMV DNA terminase complex inhibitor, Letermovir represents a novel class of antiviral agents with a unique mechanism of action and minimal cross-resistance.

At Yikang Chemical, we supply high-purity Letermovir API and research-grade compounds, supporting both preclinical research and commercial formulation projects across global pharmaceutical markets.


Product Information – Letermovir

  • Product Name: Letermovir
  • CAS Number: 917389-32-3
  • Molecular Formula: C29H28F4N4O4
  • Molecular Weight: 588.55 g/mol
  • Appearance: Off-white to pale yellow solid
  • Purity: ≥99% (HPLC)
  • Synonyms: AIC246, Prevymis™

Letermovir selectively targets the viral terminase complex subunits (UL51, UL56, UL89), inhibiting viral DNA packaging and reducing CMV replication in immunocompromised patients.


🧪 Applications & Therapeutic Uses

  • Antiviral therapy for CMV prevention
  • Clinical trials and formulation development
  • Research on herpesvirus inhibitors
  • Raw material for antiviral drug manufacturing

Approved by FDA and EMA, Letermovir is considered the first-in-class terminase inhibitor with low toxicity and oral bioavailability, offering significant safety benefits over traditional CMV drugs like ganciclovir or foscarnet.


🏭 Why Choose Yikang Chemical for Letermovir?

  • GMP-Grade Quality – Consistent batch-to-batch reproducibility
  • Technical Support – Full COA, MSDS, NMR, and impurity profile
  • Flexible Supply – From milligram R&D quantities to commercial scale
  • Global Logistics – Fast delivery with full export compliance
  • Custom Synthesis – Available for related intermediates and analogs

Whether you’re working in antiviral drug research, formulation R&D, or commercial production, Yikang Chemical is your trusted supplier of Letermovir API and intermediates.


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📦 Packaging & Delivery Options

  • Standard Packaging: Foil bag or HDPE container
  • Quantity: From 1g to multi-kilogram bulk
  • Labeling: Meets ICH & GHS regulatory standards
  • Shipping: FedEx, DHL, or bulk air/sea freight
  • Storage: Store at 2–8°C, away from light and moisture

📞 Get in Touch for Quote or Sample

Looking for a reliable source of Letermovir (CAS 917389-32-3) for pharmaceutical use or research purposes? Contact us today for detailed specifications, pricing, and logistics support. We’re ready to supply excellence – from molecule to market.

🌐 Website: www.yikanghuagong.com
📧 Email: yikangmelody@163.com

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