Desalted Form of Tadalafil Intermediate 2 (CAS 171595-41-1) – High-Purity Non-Hydrochloride Version for API Synthesis

Tadalafil Intermediate 2 – Desalted Form (CAS 171595-41-1) is a key non-hydrochloride intermediate in the synthetic pathway of Tadalafil API, a well-known PDE5 inhibitor used to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). This non-salt (desalted) form offers improved compatibility with specific synthetic protocols where the presence of chloride ions is not desired or where further salt formation steps are controlled downstream.

At Yikang Chemical, we provide high-purity Tadalafil Intermediate 2 (non-hydrochloride form) in research and production scales, supporting both generic drug synthesis and customized process optimization.


Product Details – Tadalafil Intermediate 2 (Desalted Form)

  • Product Name: Tadalafil Intermediate 2 (Desalted Form, Non-HCl)
  • CAS Number: 171595-41-1
  • Molecular Formula: C14H18N2O4
  • Molecular Weight: 278.30 g/mol
  • Appearance: Off-white to pale yellow solid
  • Purity: ≥98% (HPLC)
  • Synonyms: Non-hydrochloride Tadalafil Intermediate 2, desalted tadalafil intermediate, tadalafil base intermediate

This intermediate is commonly used in the cyclization and condensation steps in tadalafil synthesis, and its desalted form allows better control of downstream reaction conditions and salt formation.


🧪 Applications & Uses

  • Synthesis of Tadalafil API
  • PDE5 inhibitor research
  • Pharmaceutical formulation R&D
  • Salt-free synthesis routes and process optimization

The non-HCl version is particularly valued by manufacturers looking to avoid counter-ion contamination, improve purity profiles, and develop proprietary synthesis processes.


🏭 Why Yikang Chemical is Your Trusted Source

  • High Purity & Stability – ≥98% purity, low moisture, low chloride
  • Flexible Supply Options – From lab samples to commercial batch quantities
  • Full Documentation – COA, MSDS, synthesis route available
  • Custom Synthesis Support – Route development and impurity control assistance
  • Global Delivery – Compliant export services with fast dispatch

Our desalted tadalafil intermediate has been widely adopted in generic tadalafil production and CDMO synthesis platforms for regulated and emerging markets.


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📦 Packaging & Delivery Information

  • Packaging Options: Aluminum foil bag, sealed HDPE bottle, or fiber drum
  • MOQ: 100g for R&D; scalable to multi-kilogram batches
  • Storage: Store in a cool, dry, sealed container away from light
  • Logistics: FedEx, DHL, air cargo, sea freight with full customs documentation

📞 Contact Us Now for Sample or Technical Inquiry

Looking for a non-hydrochloride tadalafil intermediate with high purity and reliable batch consistency? At Yikang Chemical, we help API manufacturers and researchers achieve better efficiency, compliance, and cost control in their tadalafil synthesis workflows.

🌐 Website: www.yikanghuagong.com
📧 Email: yikangmelody@163.com

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