Sunitinib malate, CAS number 341031-54-7, is a high-performance oral multi-targeted receptor tyrosine kinase (RTK) inhibitor. It plays a pivotal role in the treatment of various solid tumors, including renal cell carcinoma (RCC), gastrointestinal stromal tumors (GIST), and pancreatic neuroendocrine tumors (pNET). As a leading API provider, Yikang Chemical (https://yikanghuagong.com/) offers premium-grade Sunitinib malate to support global pharmaceutical manufacturing and oncology drug development.
What is Sunitinib Malate?
Sunitinib malate is the malate salt form of sunitinib, a small-molecule kinase inhibitor that targets multiple signaling pathways involved in tumor proliferation and angiogenesis. It is a key component in targeted cancer therapies due to its ability to inhibit VEGFR, PDGFR, KIT, FLT3, and RET kinases.
Chemical Profile:
- CAS No.: 341031-54-7
- Molecular Formula: C22H27FN4O2 · C4H6O5
- Drug Classification: Antineoplastic agent, Tyrosine kinase inhibitor
- Brand Name: Sutent
Therapeutic Applications
Sunitinib malate is globally approved for the treatment of:
- Renal Cell Carcinoma (RCC): As a first-line or second-line therapy for advanced/metastatic kidney cancer.
- Gastrointestinal Stromal Tumors (GIST): For imatinib-resistant or -intolerant cases.
- Pancreatic Neuroendocrine Tumors (pNET): To slow tumor progression.
Mechanism of Action
Sunitinib malate works by:
- Inhibiting multiple RTKs responsible for tumor cell proliferation.
- Blocking angiogenesis by targeting VEGF and PDGF receptors.
- Interrupting pathways that sustain tumor growth and metastasis.
This multi-targeted approach makes it an ideal API for modern targeted therapies.
Yikang Chemical: Quality API Supplier for Sunitinib Malate
Why choose us?
- GMP-Compliant Production: Manufactured under rigorous pharmaceutical GMP guidelines.
- High Purity and Stability: Consistent quality ideal for formulation and regulatory submission.
- Advanced Analytical Testing: Including HPLC, MS, and NMR for structural verification and impurity profiling.
- Worldwide Logistics: Reliable and fast shipping options tailored to your region.
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Let’s Collaborate
Yikang Chemical is dedicated to driving innovation in cancer treatment by supplying high-quality APIs like Sunitinib malate. For more information, documentation, or sample requests, visit our official website: https://yikanghuagong.com/
Partner with us to bring powerful cancer therapies to patients worldwide.
